The UC Irvine Transgenic Mouse Facility (TMF) is a core facility that provides services on a recharge basis for making, breeding, genotyping, importing, and preserving genetically-modified mice and embryonic stem cells. In addition to academic clients at UCI, we also service academic investigators at several other sister UC-campuses and numerous other universities throughout the USA as well as providing these services to commercial clients.
Got a question? Email the TMF - we're here to help!
"CRISPR" Cas9/gRNA genome editing services
In certain cases CRISPR Cas9/gRNA mediated gene editing can accelerate projects to modify the mouse genome. As of October 2016, the TMF has successfully conducted 26 independent projects to modify the mouse genome via use of Cas9/gRNA. See the Cas9/gRNA Mediated Genome Engineering Services page for details.
Of interest to TMF and Cancer Center users
How can we assist you ?
- Finding and importing mice
- Need to import or export mice? Use Mustrac - an on-line tool developed at UCI
- Making mutant mice
- Designing a targeting vector
- What strain of mice did this ES cell line come from? (PDF)
The TMF is a Shared Resource funded in part by the Chao Family Comprehensive Cancer Center Support Grant (P30CA062203) from the National Cancer Institute, by Strategic Partnerships with various UCI Offices and Schools, and by established chargeback systems.